Pure Ursodeoxycholic acid

Main Features

Ursodeoxycholic acid powder is the raw material form of the drug Ursodeoxycholic Acid (UDCA), usually being a high-purity white or off-white crystalline powder.

• The essence is raw materials: It is the starting point for pharmaceutical production, which are then further processed into the final capsules, tablets, and other preparations that patients consume.
• The purity requirements are extremely high: As a pharmaceutical ingredient, its purity, impurity content, crystal form, etc. must comply with strict national pharmaceutical standards (such as the “Chinese Pharmacopoeia”).
• Non-directly consumed products: They must not be purchased directly as health supplements or medicines and should not be taken by dissolving in water. Individuals cannot accurately determine the dosage and purity, and using them without authorization poses serious safety risks (such as liver damage, ineffective treatment, impurity hazards, etc.).
• Legal Use: Only by qualified pharmaceutical manufacturing enterprises, under strict quality control, for the production of compliant medicines.

Core summary: Ursodeoxycholic acid powder is a raw material used in the pharmaceutical industry, not a consumer product.

What are the applications of ursodeoxycholic acid?

Ursodeoxycholic acid is a prescription drug. Its application and main efficacy mainly revolve around the liver and gallbladder system. The details are as follows:

Main Clinical Applications (Efficacy and Uses)

1.Treatment of cholestatic liver diseases (primary indication)

• Primary biliary cholangitis: First-line treatment drug, which can improve liver function indicators (such as reducing alkaline phosphatase and γ-glutamyl transferase), slow down disease progression, and prolong the survival period without liver transplantation.
• Other cholestasis: It can also be used to treat intrahepatic cholestasis during pregnancy, cystic fibrosis-related liver diseases, and drug-induced cholestasis, etc. (Evaluation by a doctor is required).

2. Dissolving cholesterol gallstones

Applicable to pure cholesterol gallstones in the gallbladder with normal gallbladder function and which can be seen on X-ray (typically with smaller stone diameters), and for patients who are not suitable or unwilling for surgery. It is ineffective for calcified or pigmented stones.

3. Other applications (under the guidance of a doctor for exploratory use)

· Assist in the treatment of non-alcoholic fatty liver disease.

· Prevent certain complications of bile stasis that may occur after liver transplantation.

Core Pharmacological Effects (Mechanism of Action)

• Alternative hepatotoxic bile acids: Replace the hydrophobic and cytotoxic bile acids in the body, thereby reducing the damage to liver cells and bile duct cells.

• Promote bile secretion: Stimulate the liver cells to secrete bile rich in bicarbonate, improve bile flow, and facilitate the elimination of jaundice.

• Protect liver cells: Exhibits anti-apoptotic, anti-inflammatory and membrane-stabilizing effects.

• Reduce cholesterol saturation: Inhibit the absorption of cholesterol in the intestines, lower the cholesterol saturation in bile, thereby facilitating the dissolution of cholesterol stones.